By Maria M. Picken MD PhD FASN, Ahmet Dogan, Guillermo A. Herrera
The moment variation of this article provides an outline of the latest advancements during this zone together with medical presentation, etiology, pathogenesis, and differential analysis. the explanation for varied remedies, together with transplantation, is mentioned and tissue prognosis (its pitfalls and methods for fending off them) and laboratory help are incorporated. The involvement of all significant organ platforms together with renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central fearful procedure, tender tissue, pores and skin, lymph node/spleen and bone marrow pathology is usually covered.
Amyloid and comparable problems, moment Edition may be priceless to really good and normal pathologists in addition to cytopathologists. different doctors can also take advantage of this concise replace at the systemic amyloidoses.
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Additional info for Amyloid and Related Disorders: Surgical Pathology and Clinical Correlations
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3;q32) is a recurrent genetic lesion in primary amyloidosis. Am J Pathol. 2001;158:1599–603. 110. Bochtler T, et al. Hyperdiploidy is less frequent in AL amyloidosis compared with monoclonal gammopathy of undetermined signiﬁcance and inversely associated with translocation t(11;14). Blood. 2011;117:3809–15. 111. Bochtler T, et al. Gain of chromosome 1q21 is an independent adverse prognostic factor in light chain amyloidosis patients treated with melphalan/dexamethasone. Amyloid. 2014;21:9–17. 112.